Virological control, inmunological stage and stratification of diabetogenesis in a geriatric cohort with HIV in Latin America

06 May 2024, Version 1
This content is an early or alternative research output and has not been peer-reviewed by Cambridge University Press at the time of posting.

Abstract

Introduction: In HIV-positive patients, the risk of diabetes and the existence of metabolic syndrome have been discounted. Goals: Assessing the prevalence of metabolic syndrome and contrasting the FINDRISC-based diabetes mellitus risk classification in HIV-positive individuals. Methodology: from January 2016 to December 2018, 760 persons with HIV were included in a cross-sectional study. The ATP-III criteria were used to assess the existence of metabolic syndrome, and the FINDRISC was used to assess the diabetes risk score. Information gleaned from health records was connected. Measures of association in the inferential statistical analysis will be odds ratios. The Mann-Whitney test or Student's T test was utilized while dealing with numerical or quantitative variables. Findings: Of the comorbidities, smoking accounted for 66.8%, followed by hypercholesterolemia (52%), and arterial hypertension (32%). The results of the FINDRISC showed that 646 patients (85%) had low risk, 98 patients (12.8%) had moderate risk, and 16 patients (2.2%) had high risk. There was statistical evidence of a link between a relatively high FINDRISC and a low CD4 count of fewer than 200 cells and a high viral load. Conclusions: Among individuals infected with HIV, a significant proportion of patients had both a moderate and high risk of diabetes. Given that cardiovascular risk factors are often linked to negative outcomes of this kind, it is important to take them into consideration. Of particular, patients with HIV may be at increased risk of developing diabetes.

Keywords

HIV
Diabetes
Prevalence

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