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Predicting and Experimentally Validating Hot-Spot Residues at Protein-Protein Interfaces

Amaurys Ibarra, Gail J. Bartlett, Zsofia Hegedus, Som Dutt, Fruzsina Hobor, Katherine Horner, Kristina Hetherington, Kirstin Spence, Adam Nelson, Thomas Edwards, Derek N Woolfson, Richard Sessions, Andrew Wilson

Version 1 posted 03 July 2019

791

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Theoretical and Computational Chemistry

Working Paper

Integrated Docking and Enhanced Sampling Based Selection of Repurposing Drugs for SARS-CoV-2 by Targeting Host Dependent Factors

Amit Kumawat, Sadanandam Namsani, Debabrata Pramanik, Sudip Roy, Jayant K. Singh

Version 1 posted 15 December 2020

569

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Biological and Medicinal Chemistry

Working Paper

A Small Molecule Inhibitor with Elongated Residence Time Blocking the Cytolytic Effects of the Pore-Forming Toxin Pneumolysin

Umer Bin Abdul Aziz, Marcel Bermudez, Maren Mieth, Ali Saoud, Thomas Rudolf, Christoph Arkona, Christoph Böttcher, Kai Ludwig, Andreas Hocke, Gerhard Wolber, Jörg Rademann

Version 1 posted 15 June 2022

318

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Biological and Medicinal Chemistry

Working Paper

Rapid Flow-Based Synthesis of Post-Translationally Modified Peptides and Proteins: A Case Study on MYC’s Transactivation Domain

Elyse T. Williams, Kevin Schiefelbein, Matthias Schuster, Ikhlas M. M. Ahmed, Marije De Vries, Rebecca Beveridge, Oliver Zerbe, Nina Hartrampf

Version 1 posted 27 February 2024

284

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Biological and Medicinal Chemistry

Working Paper

Computer- and NMR-aided design of small-molecule inhibitors of the Hub1 protein

Ewa Surmiak, Katarzyna Kubica, Atilio Reyes Romero, Jacek Plewka, Ismael Rodriguez, Katarzyna Magiera-Mularz, Alexander Domling, Tad Holak

Version 1 posted 27 January 2022

181

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Biological and Medicinal Chemistry

Review

Recent advances in studying Toll-like receptors with the use of computational methods

Maria Bzówka, Weronika Bagrowska, Artur Góra

Version 3 posted 14 March 2023

159

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Biological and Medicinal Chemistry

Working Paper

Peptide inhibitors of the dyskerin/dyskerin protein-protein interaction, a cancer target highlighted by Dyskeratosis Congenita mutations in ribonucleoproteins of telomerase.

Suzanne van Wier, Zoe Goddard, Ellen Hyde, Marco Cominetti, Mark Searcey, Andrew Beekman

Version 1 posted 20 March 2024

91

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Biological and Medicinal Chemistry

Working Paper

An Organometallic Strategy for Assembling Atomically Precise Hybrid Nanomaterials

Julia M. Stauber, Elaine A. Qian, Yanxiao Han, Arnold L. Rheingold, Petr Král, Daishi Fujita, Alexander Spokoyny

Version 1 posted 10 September 2019

980

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Biological and Medicinal Chemistry

Working Paper

A system for the evolution of protein-protein interaction inducers

Jeffrey Dewey, Saara-Anne Azizi, Vivian Lu, Bryan Dickinson

Version 1 posted 22 June 2021

844

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Biological and Medicinal Chemistry

Working Paper

Fluorine-induced polarity increases inhibitory activity of BPTI towards chymotrypsin

Jakob Leppkes, Nicole Dimos, Bernhard Loll, Thomas Hohmann, Michael Dyrks, Ariane Wieseke, Bettina G. Keller, Beate Koksch

Version 2 posted 05 April 2022

163

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Refine Search

31 results in Protein-Protein Interactions in Keywords: Protein-Protein Interactions

Predicting and Experimentally Validating Hot-Spot Residues at Protein-Protein Interfaces

Integrated Docking and Enhanced Sampling Based Selection of Repurposing Drugs for SARS-CoV-2 by Targeting Host Dependent Factors

A Small Molecule Inhibitor with Elongated Residence Time Blocking the Cytolytic Effects of the Pore-Forming Toxin Pneumolysin

Rapid Flow-Based Synthesis of Post-Translationally Modified Peptides and Proteins: A Case Study on MYC’s Transactivation Domain

Computer- and NMR-aided design of small-molecule inhibitors of the Hub1 protein

Recent advances in studying Toll-like receptors with the use of computational methods

Peptide inhibitors of the dyskerin/dyskerin protein-protein interaction, a cancer target highlighted by Dyskeratosis Congenita mutations in ribonucleoproteins of telomerase.

An Organometallic Strategy for Assembling Atomically Precise Hybrid Nanomaterials

A system for the evolution of protein-protein interaction inducers

Fluorine-induced polarity increases inhibitory activity of BPTI towards chymotrypsin

31 results in Keywords: Protein-Protein Interactions