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Defining the molecular architecture, metal dependence, and distribution of metal-dependent class II sulfofructose-1-phosphate aldolases

Mahima Sharma, Arashdeep Kaur, Niccolay Madiedo Soler, James Lingford, Ruwan Epa, Ethan Goddard-Borger, Gideon Davies, Spencer Williams

Version 1 posted 08 August 2023

131

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Catalysis

Working Paper

Site-selective deuteration of amino acids through dual protein catalysis

Tyler Doyon, Andrew Buller

Version 1 posted 09 March 2022

354

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Biological and Medicinal Chemistry

Working Paper

In Vitro Reconstitution and Kinetic Characterization of the Essential Condensation Enzymes Involved in Prodiginine and Tambjamine Biosynthesis

Katherine J. Picott, Julie A. Deichert, Ella M. deKemp, Avena Ross

Version 1 posted 19 April 2019

437

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Inorganic Chemistry

Working Paper

A Dynamic Substrate is Required for MhuD-catalyzed Degradation of Heme to Mycobilin

Biswash Thakuri, Bruce O'Rourke, Amanda Graves, Matthew Liptak

Version 4 posted 05 March 2021

710

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Biological and Medicinal Chemistry

Working Paper

An Epoxide Intermediate in Glycosidase Catalysis

Lukasz F. Sobala, Gaetano Speciale, Sha Zhu, Lluís Raich, Natalia Sannikova, Andrew J. Thompson, ZALIHE HAKKI, Dan Lu, Saeideh Shamsi Kazem Abadi, Andrew R. Lewis, Victor Rojas-Cervellera, Ganeko Bernardo-Seisdedos, Yongmin Zhang, Oscar Millet, Jesús Jiménez-Barbero, Andrew J. Bennett, Matthieu Sollogoub, Carme Rovira, Gideon J. Davies, Spencer Williams

Version 1 posted 04 September 2019

746

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Catalysis

Working Paper

Glutamate “flick” enables proton tunneling during fast redox biocatalysis

Stephen B. Carr, Wangzhe Li, Kin Long Wong, Rhiannon M. Evans, Sophie E. T. Kendall-Price, Kylie A. Vincent, Philip A. Ash

Version 1 posted 06 May 2024

114

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Biological and Medicinal Chemistry

Working Paper

The Catalytic Acid-Base in GH109 Resides in a Conserved GGHGG Loop and Allows for Comparable α-Retaining and β-Inverting Activity in an N-Acetylgalactosaminidase from Akkermansia Muciniphila

David Teze, Bashar Shuoker, Evan Kirk Chaberski, Ruth Sonja Kunstmann, Folmer Fredslund, Günther H.J. Peters, Eva Nordberg Karlsson, Ditte Hededam Welner, Maher Abou Hachem

Version 1 posted 21 October 2019

632

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7 results in Enzyme Mechanism in Keywords: Enzyme Mechanism

Defining the molecular architecture, metal dependence, and distribution of metal-dependent class II sulfofructose-1-phosphate aldolases

Site-selective deuteration of amino acids through dual protein catalysis

In Vitro Reconstitution and Kinetic Characterization of the Essential Condensation Enzymes Involved in Prodiginine and Tambjamine Biosynthesis

A Dynamic Substrate is Required for MhuD-catalyzed Degradation of Heme to Mycobilin

An Epoxide Intermediate in Glycosidase Catalysis

Glutamate “flick” enables proton tunneling during fast redox biocatalysis

The Catalytic Acid-Base in GH109 Resides in a Conserved GGHGG Loop and Allows for Comparable α-Retaining and β-Inverting Activity in an N-Acetylgalactosaminidase from Akkermansia Muciniphila

7 results in Keywords: Enzyme Mechanism