Organic Chemistry

Synthesis and Properties of Palladium–Triazolopyridinylidene: Catalyst for Cross-Coupling Using Chloroarenes and Nitroarenes



The synthesis and catalytic activity of triazolopyridinylidene as a novel abnormal N-heterocyclic carbene (aNHC) ligand was described. The evaluation of physical properties using X-ray crystallographic analysis and infrared spectroscopy revealed that these triazolopyridinyli-denes have a high electron-donating ability to the metal center. Aapplication of triazolopyridinylidenes to palladium-catalyzed cross-coupling of chloroarenes and nitroarenes showcased its ability to activate C–Cl and C–NO2 bonds.


Thumbnail image of 20220520Iizumi_TriPy.pdf

Supplementary material

Thumbnail image of SI_NHC_TriPy_iizumi_20220520_IK.pdf
Supporting Information
Experimental procedures and spectroscopic data for compounds in-cluding 1H-, 13C-, and 19F-NMR spectra and crystallographic data (PDF).

Supplementary weblinks

Yamaguchi Lab
J. Yamaguchi lab