Mild and Chemoselective Phosphorylation of Alcohols Using a PSI-Reagent

19 August 2021, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

An operationally simple, scalable, and chemoselective method for the direct phosphorylation of alcohols using a P(V)-approach based on the PSI-reagent platform is disclosed. The method features a broad substrate scope of utility in both simple and complex settings and provides access to valuable phosphorylated alcohols that would be otherwise difficult to access.

Keywords

phosphorylation
phosphorus
P(V)
organic methodology

Supplementary materials

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Supporting information
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copies of spectra, characterization, and procedures
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