Treatment of COVID-19 patients: Justicia adhatoda leaves extract is a strong remedy for COVID-19 – Case report analysis and docking based study

27 March 2020, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

To find immediately applicable drug for the treatment of COVID-19 positive patients, a plausible life cycle of this virus is proposed from the analysis of few case reports. On the basis of this proposal and symptomatic similarities few common drug-molecules are tested as protease inhibitor and replicase inhibitor of COVID-19 virus using COVID-19 Docking Server. It is observed that anisotine and vasicoline of Justicia adhatoda and Pemirolast are very good inhibitors. As all these three compounds are market available drugs, immediate clinical trial is plausible which may lead to the golden success against the present pandemic. We prescribed different drugs for different purpose and stages of viral infection.

Key words: COVID-19, Structure of COVID-19, Infection mechanism of COVID-19, Model drugs for COVID-19, Docking study.

Keywords

COVID-19
Structure of COVID-19
Infection mechanism of COVID-19
Treatment of COVID-19
Anisotine
Vasicoline
Pemirolast
Molecular docking

Supplementary materials

Title
Description
Actions
Title
toc-f
Description
Actions
Title
anisotine-prot
Description
Actions
Title
anisotine-rdrp
Description
Actions
Title
dock-aniso-prot
Description
Actions
Title
dock-aniso-rdrp
Description
Actions
Title
dock-pemir-prot
Description
Actions
Title
dock-pemir-rdrp
Description
Actions
Title
dock-vasico-prot
Description
Actions
Title
dock-vasico-rdrp
Description
Actions
Title
meth-prop-qun-prot
Description
Actions
Title
pemirolast-prot
Description
Actions
Title
pemirolast-rdrp
Description
Actions
Title
vasicoline-prot
Description
Actions
Title
vasicoline-rdrp
Description
Actions

Supplementary weblinks

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